Junior Brett Comer scored 10 points as Florida Gulf Coast pulled away after halftime on a 15-5 clip to defeat Lipscomb 75-62 Wednesday night.
The scoring burst in the first 4 minutes of the second half boosted Comer to a game-high 24 points, matching his career best, before he sat out the final 10:41 with four fouls.
The Eagles (8-7, 2-0 Atlantic Sun) start conference play 2-0 for the first time in program history. Bernard Thompson and DaJuan Graf each added 13 points for FGCU, a career high for Graf.
Twins Martin and Malcolm Smith led Lipscomb (5-8, 0-2) with 20 and 15 points, respectively. The Bisons were outrebounded 41-31, but were not effective from three-point range, hitting just 9-of-25. J.C. Hampton hit four threes for 14 points.
On FCGU's first possession, Comer found Bernard Thompson on the wing for three-pointer to collect his 500th career assist.
Making his first start of the year, Eric McKnight corralled a career-best 10 rebounds and added six points while rejecting three shots in the Iowa State transfer's best all-around game of the season.
Chase Fieler grabbed 10 boards, his fourth double-figure rebounding performance in the last seven games, while also tallying six points.
With the win, FGCU runs its record over the past 23 games at Alico Arena to 21-2, including a 12-1 mark in the last 13 contests dating back to last year.
In all six of their previous seasons as an A-Sun member the Eagles began each year 1-1, with the exception of 2010-11 when they opened 0-2.
FGCU travels to Stetson to take on the Hatters at 1 p.m. on Sunday.